The most common adverse events were paresthesias , hyperglycemia , infection , and constipation .. Adverse EventsThe most serious adverse events with Gemzar plus paclitaxel for the treatment of patients with MBC were neutropenia , alopecia , leucopenia , anemia , fatigue , thrombocytopenia , ALT elevation and sensory neuropathy . The most common adverse events were nausea , fatigue , myalgia and vomiting . The most serious adverse events with gemcitabine for the first-line treatment of patients with pancreatic cancer were neutropenia , alkaline phosphatase elevation , AST , nausea / vomiting , ALT elevation , anemia , leukopenia , thrombocytopenia , bilirubin increase and pain .
The study evaluated results from 411 Caucasian patients compared with 117 non-Caucasian patients. Based on this analysis, race has no statistically significant effect on the efficacy parameters . Non-Caucasian patients had lower grade 3/4 toxicities, including neutropenia , anemia , fatigue and nausea.
Obasaju CK, Kulkarni P, 2007 effect of race on the safety and efficacy of pemetrexed therapy in locally advanced and metastatic non – small cell lung cancer American Society of Clinical Oncology Annual Meeting. Devastatingilly and Company.. The ALIMTA study reviewed a post-hoc analysis of pooled data from six previous studies, including a Phase III in a second-line setting and five Phase II clinical trials in first-line setting.Study, triple-negative published online in which journal Cancer, saw five hundred and eighty-one African American women and 1,008 white females with a breast cancer in Henry Ford Health System Detroit, up 75 African women diagnosis in Komfo Anokye Teaching Hospital of Ghana diagnosed with.
Researchers from the University of Michigan Comprehensive Cancer Centre noted that in women breast cancer, 82 % of African women were triple negative, 26 % of African Americans and 16 % of the white Americans Been.