Principal investigator at Los Angeles Biomedical Study Institute.

The outcomes of the study reveal that adding a common antibiotic – azithromycin – to the most common daily treatment for COPD reduced the occurrence of acute exacerbations by 27 percent and tended to improve the quality of life for COPD patients. The results of the analysis, funded by the National Center, Lung, and Blood Institute , part of the National Institutes of Wellness, appeared in the Aug. 25 issue of the New England Journal of Medication. ‘This important study increases a growing number of approaches that decrease the rate of recurrence of COPD ailments,’ said Dr.Baseline characteristics were compared between research groups with the use of the chi-square test, Fisher’s exact check, Wilcoxon rank-sum check, and two-sample t-exams. The incidence of important safety outcomes was compared with the use of Fisher’s exact test. Analyses of main and secondary outcomes were performed by using time-to-event methods, based on the intention-to-treat basic principle, and occurrences of outcomes were weighed against the usage of hazard ratios and 95 percent confidence intervals. Two-sided P ideals were obtained from likelihood ratio checks from Cox proportional-hazards regression analyses. The Cox models contained a term representing study-group assignment plus terms for the following prespecified variables: assignment to the intensive glycemic intervention, the seven clinical-center networks, and the absence or existence of a previous cardiovascular event.