A 12-year-old girl with migraines We ask an expert how she would manage this whole case of a woman with recurrent migraines. Case scenario I recently saw a 12-year-old female who has been having common type migraines on average once every fourteen days for the past 8 weeks. Does she have to have any investigations? Is it appropriate to use the same type of medication in an adolescent that you might use in an adult having recurrent migraines? Commentary Migraine is quite common in childhood and takes its large %age of the outpatient practice of general paediatric neurologists. It is a gratifying condition to take care of because most children could be helped.This lesser concentration requirement could reduce frequent dose requirements and the high costs of anti-C5 antibody therapy. Finally, results had been presented from a report comparing subcutaneous doses of ALN-CC5 to a higher, intravenously administered dosage of an anti-C5 mAb in a mouse anti-collagen antibody induced arthritis model. Results demonstrated that C5 knockdown with ALN-CC5 was as effective as the anti-C5 antibody in reducing clinical disease activity, with both treatments resulting in an approximately 80 percent decrease in scientific disease activity score.