Resistance screening was performed in individuals receiving sofosbuvir who didn’t have a virologic response . We conducted analyses of nucleotide changes in the HCV NS5B gene in samples gathered at baseline and during virologic failure. DDL Diagnostics Laboratory performed NS5B populace and amplification sequencing, and WuXi AppTec performed deep-sequencing assays to characterize virologic level of resistance. Primary End Point In the two studies, the principal efficacy end point was a sustained virologic response, which was thought as an HCV RNA level below the lower limit of quantification, at 12 weeks following the end of treatment.We anticipate welcoming Evalve as an integral component of Abbott’s vascular business. Patients in European countries have benefited from access the MitraClip technology because it received CE Tag last year, said Ferolyn Powell, president and ceo of Evalve, who will continue to lead the Evalve group and will report to Hance after the acquisition closes. We anticipate becoming a component of Abbott and functioning collectively to accelerate our business and broaden our global reach to patients around the world with our minimally invasive technologies. Under the conditions of the agreement, Abbott shall find the remaining 90 % of outstanding equity of Evalve, Inc.